Cheap flights from Mayaguez to Panama City

Flights tailored to your budget

Selected dates may not give results due to COVID-19. We suggest you change the dates.
Multi-city Round trip One way
Round trip
One way
Multi-city
From
No results match your search criteria
To
No results match your search criteria
{{ weekDay }}
Dates
{{ panel.label }}
Looking for a one-way flight?

Flexible dates can save you money

Explore nearby dates to find lower fares

{{ fromDate | dateToLongNamedDate }}
?
Flexible dates
Depart {{ flexibleFromDateLabel }}
{{ option.label }}
?
Return {{ flexibleToDateLabel }}
{{ option.label }}
Passengers / Class
Number of passengers
Adults
{{ adults }}
Children
{{ children }}
Infants
{{ infants }}
Class
Economy
Available for Economy only
New Multi-city experience

Discover a new Multi-city search experience from Jetcost, designed to handle more complex itineraries. By continuing, you’ll be taken to a dedicated page powered by Kiwi.com.
How do we get the info you see here? Please note that we offer an online comparison service and that all information and prices regarding services and/or products available on our website are provided by our third-party partners. We do our best to show you up-to-date information, but please note that we are not responsible for the completeness or accuracy of the information published, so please check all conditions carefully on the website of the partner before making a booking. Please check our Terms and Conditions for more details. Read more

How to get the best price from Mayaguez to Panama City?

Depending on when you travel and how far in advance you book, fares between Mayaguez and Panama City can differ a lot.

Pick a travel date to see today’s available fares.

Search engines like Jetcost can highlight price changes in just seconds. For example, some users find better prices by flying on one day of the week over another — try several searches to spot the cheapest day.

Exploring all airports near Mayaguez and Panama City

Checking all the airports available in the area can give you more departure and arrival options for your trip.

  • Airports in Mayaguez: Mayaguez - Eugenio Maria de Hostos is currently the only one operating.
  • Airports in Panama City: Panama City is served by 2 airports - Pacífico International Airport, Paitilla.

Looking at expected traffic to the airport can help avoid surprises on departure day. On busy routes, flying from a quieter airport might also save you money.

Flights from Mayaguez - Eugenio Maria de Hostos to Panama City - Tocumen

Smart ways to search flights from Mayaguez to Panama City

Use Jetcost to view tailored results based on what you care about — time, duration, number of stops, or even your preferred booking agency. Results include carriers like Easyjet, Ryanair, British Airways, and more.

Other popular destinations

Flying to Panama? Other travelers also searched: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

Prefer non-stop flights? Just activate the filter to skip unnecessary layovers. If your dates are flexible, you can also explore different departure and return combinations to find the best fit.
Frequently Asked Questions

Frequently asked questions about flights from Mayaguez to Panama City.

How much does an airline ticket from Mayaguez to Panama City cost?

Flight prices can vary a lot depending on the period and destination. At the moment, this information is not available for flights from Mayaguez to Panama City.

How far is Mayaguez from Panama City?

Mayaguez is about 1668 km from Panama City.

What are the airports in Panama City?

Panama City has 2 airports: Pacífico International Airport, Paitilla.

What are the airports in Mayaguez?

Mayaguez has one airport: Mayaguez - Eugenio Maria de Hostos.

What are the most popular cities in Panama?

The most popular cities in Panama according to our users' searches are: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

When should I book a flight from Mayaguez to Panama City?

This information is not available at the moment.

What is the cheapest month to fly from Mayaguez to Panama City?

This information is not available at the moment.

What is the most expensive month to fly from Mayaguez to Panama City?

This information is not available at the moment.

What is the best day of the week to fly from Mayaguez to Panama City?

This information is not available at the moment.