How much should you expect to spend for a flight from Panama City - Pacífico International Airport to Santiago de los Caballeros?

Flight prices from Panama City to Santiago change depending on demand and time of booking.

Pick a travel date to see today’s available fares.

Studies show that flying midweek — like on a Tuesday or Wednesday — can be cheaper than weekend flights. Still, airfares change frequently, so check updated prices on Jetcost.

Are there multiple airports in Panama City and Santiago?

If your departure or arrival city has more than one airport, it's worth comparing all of them for timing and pricing.

• Airports in Panama City: 2 airports are active in Panama City - Pacífico International Airport, Paitilla.
• Airports in Santiago: Santiago - Cibao International is the only airport currently running.

If you're traveling with a group or bulky luggage, look into parking or transport options. Alternative airports may offer faster transfers or better rates.

Find the best flight from Panama City - Pacífico International Airport to Santiago de los Caballeros

With Jetcost, you can filter results by flight time, airline, price range, and layovers. Choose direct or connecting flights, round-trip or one-way, and compare offers from Ryanair, Easyjet, British Airways, and more.

Other popular destinations

Searching for flights to Dominican Republic? Travelers also looked at: Puerto Plata, Punta Cana, Samaná, Santiago, Santo Domingo.

Use filters to exclude options that don’t match your budget or travel preferences and personalize your search for Panama City - Pacífico International Airport – Santiago de los Caballeros flights.